AIRE Antikörper (Middle Region)
Kurzübersicht für AIRE Antikörper (Middle Region) (ABIN950316)
Target
Alle AIRE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 64-92, Middle Region
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Spezifität
- This antibody reacts to AIRE.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human and Mouse.
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Aufreinigung
- Affinity chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) sodium azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AIRE (Autoimmune Regulator (AIRE))
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Andere Bezeichnung
- AIRE / APECED
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Hintergrund
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).Synonyms: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator
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Gen-ID
- 326
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NCBI Accession
- NP_000374
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Pathways
- Chromatin Binding
Target
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