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hTSH Antikörper

Reaktivität: Human ELISA, RIA Wirt: Maus Monoclonal TSH-116 unconjugated
Produktnummer ABIN94482
  • Target
    hTSH
    Reaktivität
    Human
    Wirt
    • 2
    Maus
    Klonalität
    • 2
    Monoklonal
    Konjugat
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 2
    • 2
    • 1
    ELISA, Radioimmunoassay (RIA)
    Verwendungszweck
    Anti-hTSH Purified
    Spezifität
    The antibody TSH-116 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain. The TSH-116 reacts with association constant 1.1 x 1011 l/mol. Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-116: hTSH (78.9), hCG (20.3), hLH (23.2), hFSH (29.9).
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Human thyrotropin.
    Klon
    TSH-116
    Isotyp
    IgG2a
  • Applikationshinweise
    RIA: The antibody TSH-116 is suitable in combination with the antibody TSH-51 for immunometric assays in the screening of neonatal hypothyroidism.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Jirkalová, Cáp, Straková, Príbysová, Plicka, Lomský: "Immunoradiometric and luminescence immunoenzymometric assay of human thyrotropin from dried blood spots for screening of neonatal hypothyroidism." in: European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, Vol. 34, Issue 10, pp. 823-7, (1997) (PubMed).

  • Target
    hTSH
    Hintergrund
    Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha nad beta.,Thyrotropin
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