Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

HLA-DP/DR Antikörper

HLA-DP/DR Reaktivität: Human FACS, IP, WB, IHC (p) Wirt: Maus Monoclonal MEM-136 unconjugated
Produktnummer ABIN94344
  • Target Alle HLA-DP/DR Produkte
    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))
    Reaktivität
    • 15
    • 5
    Human
    Wirt
    • 15
    Maus
    Klonalität
    • 15
    Monoklonal
    Konjugat
    • 4
    • 4
    • 3
    • 2
    • 2
    Dieser HLA-DP/DR Antikörper ist unkonjugiert
    Applikation
    • 15
    • 7
    • 7
    • 4
    • 3
    Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Anti-HLA-DR/DP Purified
    Spezifität
    The antibody MEM-136 recognizes a common extracellular epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    PHA-activated peripheral blood lymphocytes.
    Klon
    MEM-136
    Isotyp
    IgG1
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Western blotting: Recommended dilution: 1 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Koch, Staffler, Hüttinger, Hilgert, Prager, Cerný, Steinlein, Majdic, Horejsí, Stockinger: "T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density." in: International immunology, Vol. 11, Issue 5, pp. 777-86, (1999) (PubMed).

  • Target
    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))
    Andere Bezeichnung
    HLA-DR/DP (HLA-DP/DR Produkte)
    Hintergrund
    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
Sie sind hier:
Kundenservice