C-Peptide Antikörper

Produktnummer ABIN94267

Dieses Maus Monoklonal-Antikörper erkennt spezifisch C-Peptide in ELISA, ICC, IHC (p) und RIA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für C-Peptide Antikörper (ABIN94267)

Target: C-Peptide

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser C-Peptide Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA)

Klon: C-PEP-01

Produktdetails anti-C-Peptide Antikörper

Verwendungszweck: Anti-Hu C-peptide Purified

Spezifität: The mouse monoclonal antibody C-PEP-01 reacts specifically with C-peptide, a part of the proinsulin molecule. Proinsulin consists of three parts: C-peptide and two long strands of amino acids (alpha and beta chains, later become linked together to form the insulin molecule). No cross-reactivity with insulin or other peptide hormones or proteins was observed.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Human C-peptide conjugated to bovine serum albumin.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (paraffin sections): Recommended dilution: 2-5 μg/mL, positive control: human pancreas (islets of Langerhans).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-C-Peptide Antikörper (ABIN94267)

Koblas, Zacharovova, Berkova, Girman, Saudek: "An acidic pH and activation of phosphoinositide 3-kinase stimulate differentiation of pancreatic progenitors into insulin-producing cells." in: Transplantation proceedings, Vol. 42, Issue 6, pp. 2075-80, (2010) (PubMed).

Hilgert, Stolba, Kristofová, Stefanová, Bendlová, Lebl, Horejsí: "A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA." in: Hybridoma, Vol. 10, Issue 3, pp. 379-86, (1991) (PubMed).

Details zu C-Peptide

Target: C-Peptide

Hintergrund: From every molecule of proinsulin, one molecule of insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to insulin.,C-peptide of proinsulin