CD7 Antikörper
(1 reference)-
- Target Alle CD7 Antikörper anzeigen
- CD7
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD7 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Anti-Hu CD7 Purified
- Spezifität
- The antibody MEM-186 reacts with an extracellular epitope of CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Human acute myelogenous leukaemia cell line KG-1.
- Klon
- MEM-186
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD7 Primärantikörper
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anti-CD7 (CD7) (AA 26-134) antibody
CD7 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD7 (CD7) (AA 23-128) antibodyCD7 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 3D11F12 unconjugated
anti-CD7 (CD7) (AA 72-175) antibodyCD7 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 5B10E3 unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 2B1C9 unconjugated
anti-CD7 (CD7) antibodyCD7 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-CD7 (CD7) (AA 24-150) antibodyCD7 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD7 (CD7) (AA 21-240) antibodyCD7 Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 1B8 unconjugated
anti-CD7 (CD7) antibodyCD7 Reaktivität: Human IHC Wirt: Kaninchen Monoclonal MSVA-007R unconjugated Recombinant Antibody
anti-CD7 (CD7) (AA 72-175) antibodyCD7 Reaktivität: Human FACS, WB, ELISA, IHC Wirt: Maus Monoclonal unconjugated
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- Applikationshinweise
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Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/mL, positive tissue: spleen.
Flow cytometry: Recommended dilution: 2 μg/mL.
Western blotting: Non-reducing conditions. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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-
: "The CD3-zeta chimeric antigen receptor overcomes TCR Hypo-responsiveness of human terminal late-stage T cells." in: PLoS ONE, Vol. 7, Issue 1, pp. e30713, (2012) (PubMed).
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: "The CD3-zeta chimeric antigen receptor overcomes TCR Hypo-responsiveness of human terminal late-stage T cells." in: PLoS ONE, Vol. 7, Issue 1, pp. e30713, (2012) (PubMed).
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- Target
- CD7
- Andere Bezeichnung
- CD7 (CD7 Produkte)
- Hintergrund
- CD7 Molecule,CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.,GP40, TLA, TP41, LEU-9
- Gen-ID
- 924
- UniProt
- P09564
- Pathways
- Cell-Cell Junction Organization
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