L-Selectin Antikörper

Produktnummer ABIN94210

Dieser Maus Monoklonal Antikörper detektiert spezifisch L-Selectin in FACS. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 3+ Publikationen zitiert.

Kurzübersicht für L-Selectin Antikörper (ABIN94210)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser L-Selectin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: LT-TD180

Produktdetails anti-L-Selectin Antikörper

Verwendungszweck: Anti-Hu CD62L Purified

Kreuzreaktivität (Details): Human

Produktmerkmale: The antibody LT-TD180 reacts with an extracellular epitope of CD62L (L-selectin), a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes, it is also present on a subset of NK cells and certain hematopoietic malignant cells.

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Peripheral blood leukocytes

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-L-Selectin Antikörper (ABIN94210)

Linnebacher, Wienck, Boeck, Klar: "Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO)." in: Journal of biomedicine & biotechnology, Vol. 2010, pp. 841451, (2010) (PubMed).

Kuttruff, Koch, Kelp, Pawelec, Rammensee, Steinle: "NKp80 defines and stimulates a reactive subset of CD8 T cells." in: Blood, Vol. 113, Issue 2, pp. 358-69, (2009) (PubMed).

Simone, Zicca, Saverino: "The frequency of regulatory CD3+CD8+CD28- CD25+ T lymphocytes in human peripheral blood increases with age." in: Journal of leukocyte biology, Vol. 84, Issue 6, pp. 1454-61, (2008) (PubMed).

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: CD62L

Hintergrund: Selectin L,CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).,L-selectin, LSEL, SELL, LAM-1, LECAM1, LEU8, LNHR, LYAM1, PLNHR

Gen-ID: 6402

UniProt: P14151