L-Selectin Antikörper

Produktnummer ABIN94209

Dieses Anti-L-Selectin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von L-Selectin in FACS, IP und ICC. Geeignet für Human und Rind (Kuh). Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für L-Selectin Antikörper (ABIN94209)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reaktivität: Human, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser L-Selectin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: IVA94

Produktdetails anti-L-Selectin Antikörper

Verwendungszweck: Anti-Bov CD62L Purified

Spezifität: The antibody IVA94 reacts with an extracellular epitope of CD62L antigen (bovine). CD62L (L-selectin) is a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes, it is also present on a subset of NK cells and certain hematopoietic malignant cells.

Kreuzreaktivität (Details): Bovine

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Bovine leukocytes.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-L-Selectin Antikörper (ABIN94209)

Howard: "Ruminant cluster CD62L." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 255-6, (1997) (PubMed).

Naessens, Nthale, Muiya: "Biochemical analysis of preliminary clusters in the non-lineage panel." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 347-56, (1997) (PubMed).

Naessens, Howard, Hopkins: "Nomenclature and characterization of leukocyte differentiation antigens in ruminants." in: Immunology today, Vol. 18, Issue 8, pp. 365-8, (1997) (PubMed).

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: CD62L

Hintergrund: Selectin L,CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).,L-selectin, LSEL, SELL, LAM1, LECAM1, LEU8, LNHR, LYAM1, PLNHR

Gen-ID: 281485

UniProt: P98131