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ICAM1 Antikörper (Biotin)

ICAM1 Reaktivität: Human WB, FACS, IHC (p), IHC (fro), ICC Wirt: Maus Monoclonal 1H4 Biotin
Produktnummer ABIN94179
  • Target Alle ICAM1 Antikörper anzeigen
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Reaktivität
    • 220
    • 87
    • 38
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Human
    Wirt
    • 120
    • 119
    • 32
    • 4
    • 2
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 158
    • 119
    • 1
    Monoklonal
    Konjugat
    • 126
    • 26
    • 24
    • 21
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ICAM1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 169
    • 158
    • 64
    • 63
    • 46
    • 40
    • 36
    • 34
    • 31
    • 28
    • 24
    • 21
    • 12
    • 10
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Spezifität
    The antibody 1H4 recognizes an extracellular epitope of CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus) expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells, the expression of CD54 is upregulated by activation.
    Kreuzreaktivität (Details)
    Other not tested, Human
    Aufreinigung
    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
    Immunogen
    Raji cells and spleen cells fused with NS1 cells
    Klon
    1H4
    Isotyp
    IgG2b
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  • Applikationshinweise
    Flow cytometry: Recommended dilution: 2-5 μg/mL.
    Kommentare

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Williams, Chaudhry, Goodfellow, Lea, Evans: "Interactions of decay-accelerating factor (DAF) with haemagglutinating human enteroviruses: utilizing variation in primate DAF to map virus binding sites." in: The Journal of general virology, Vol. 85, Issue Pt 3, pp. 731-8, (2004) (PubMed).

  • Target
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Andere Bezeichnung
    CD54 (ICAM1 Produkte)
    Synonyme
    BB2 antikoerper, CD54 antikoerper, P3.58 antikoerper, Icam-1 antikoerper, Ly-47 antikoerper, MALA-2 antikoerper, ICAM antikoerper, ICAM-1 antikoerper, ICAM1 antikoerper, intercellular adhesion molecule 1 antikoerper, intercellular adhesion molecule-1 antikoerper, ICAM1 antikoerper, Icam1 antikoerper, ICAM-1 antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    Intercellular adhesion molecule 1,CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.,ICAM-1, BB2, P3.58
    Gen-ID
    3383
    UniProt
    P05362
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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