CD235ab Antikörper (N-Term)

Produktnummer ABIN94041

Dieses Anti-CD235ab-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD235ab in FACS, IHC (fro), AGG und IHC (p). Geeignet für Human.

Kurzübersicht für CD235ab Antikörper (N-Term) (ABIN94041)

Target: CD235ab (CD235a + CD235b) (Glycophorin A + B (CD235a + CD235b))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD235ab Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Aggregation (AGG), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: HIR2

Produktdetails anti-CD235ab Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-Hu CD235ab Purified

Spezifität: The mouse monoclonal antibody HIR2 recognizes an epitope within the N-terminal (extracellular) portion of CD235a (glycophorin A) and CD235b (glycophorin B). Its antigen is expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Synthetic peptide (Human, N-terminal)

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu CD235ab

Target: CD235ab (CD235a + CD235b) (Glycophorin A + B (CD235a + CD235b))

Andere Bezeichnung: CD235ab

Hintergrund: CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin.,Glycophorin A/B, GYPA/B, GPA/B, PAS-2/3, Sialoglycoprotein alpha/beta, GPSAT, GPErik, MSN blood group