CD177 Antikörper

Produktnummer ABIN94001

Der Maus Monoklonal anti-CD177 Antikörper wird verwendet zum Nachweis von CD177 in Proben von Human und Non-Human Primate. Er wurde validiert für WB, FACS und IP.

Kurzübersicht für CD177 Antikörper (ABIN94001)

Target: CD177 (CD177 Molecule (CD177))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD177 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: MEM-166

Produktdetails anti-CD177 Antikörper

Verwendungszweck: Anti-Hu CD177 Purified

Spezifität: The antibody MEM-166 reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.

Kreuzreaktivität (Details): Non-Human Primates, Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Human granulocytes

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1 μg/mL.
Western blotting: Non-reducing conditions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu CD177

Target: CD177 (CD177 Molecule (CD177))

Andere Bezeichnung: CD177

Hintergrund: CD177 Molecule,CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).,NB1, PRV1, HNA2A

Gen-ID: 57126

UniProt: Q8N6Q3