Optimal conditions should be determined byt he investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
Supplied in liquid form
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2-8 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target
Desmoglein 1 (DSG1)
Andere Bezeichnung
DSG1
Hintergrund
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, four desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. Synonyms: Monoclonal Desmoglein 1 antibody, Anti Desmoglein 1 antibody, DSG1 antibody, CDHF4 antibody, DG1 antibody, Desmosomal glycoprotein 1 antibody, Cadherin family member 4 antibody, PPKS1 antibody, SPPK1 antibody.