BMP4 Antikörper

Produktnummer ABIN934071

Zitiert in 1 Publikation. Der Maus Monoklonal anti-BMP4 Antikörper (Klon M912262) (ABIN934071) detektiert spezifisch BMP4 in WB, ELISA und InhibAb. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für BMP4 Antikörper (ABIN934071)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BMP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Klon: M912262

Produktdetails anti-BMP4 Antikörper

Aufreinigung: Protein A affinity chromatography

Immunogen: BMP4 antibody was raised in mouse using highly pure recombinant human BMP-4 as the immunogen.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: ELISA: 4-8 µg/mL, Inhibition: 0.4-0.6 µg/mL, WB: 0.25-0.5 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Referenzen für anti-BMP4 Antikörper (ABIN934071)

Calpe, Correia, Sancho-Serra, Krishnadath: "Comparison of newly developed anti-bone morphogenetic protein 4 llama-derived antibodies with commercially available BMP4 inhibitors." in: mAbs, Vol. 8, Issue 4, pp. 678-88, (2017) (PubMed).

Details zu BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Andere Bezeichnung: BMP4

Hintergrund: Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Synonyms: Monoclonal BMP4 antibody, Anti-BMP4 antibody, BMP-4 antibody, Bone Morphogenetic antibody, 4 antibody, BMP-2B antibody, DVR4 antibody.

Molekulargewicht: 31-36 kDa (predicted detection band MW)

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development