Der Ratte Monoklonal anti-Delangin-B Antikörper (Klon KT55) (ABIN933981) detektiert spezifisch Delangin-B in IF und WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus.
Kurzübersicht für Delangin-B Antikörper (ABIN933981)
Target
Delangin-B
Reaktivität
Maus
Wirt
Ratte
Klonalität
Monoklonal
Applikation
Immunofluorescence (IF), Western Blotting (WB)
Klon
KT55
Aufreinigung
Protein A affinity chromatography
Immunogen
Delangin B antibody was raised in Rat using Delangin peptide coupled carrier protein as the immunogen.
Isotyp
IgG2b
Applikationshinweise
IF: 10 µg/mL, WB: 1 µg/mL Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
Lot specific
Buffer
Supplied in PBS containing 0.1 % sodium azide as a preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.
Target
Delangin-B
Hintergrund
Delangin proteins facilitate enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Synonyms: Monoclonal Delangin B antibody, Anti-Delangin B antibody, Delangin-B antibody, NIPBL antibody, Delangin isoform B antibody.