CTCF Antikörper (C-Term)

Produktnummer ABIN933980

Der Ratte Monoklonal Anti-CTCF-Antikörper wurde für WB und IF validiert. Er ist geeignet, CTCF in Proben von Maus zu detektieren.

Kurzübersicht für CTCF Antikörper (C-Term) (ABIN933980)

Target: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CTCF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: KT70

Produktdetails anti-CTCF Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Protein G affinity chromatography

Immunogen: CTCF antibody was raised in Rat using Mouse CTCF-C-terminal fragment as the immunogen.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: IF: 1-10 µg/mL, WB: 0.1-1 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Supplied in PBS containing 0.1 % sodium azide as a preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.

Details zu CTCF

Target: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Andere Bezeichnung: CTCF

Hintergrund: The protein CTCF plays heavily in the role of repressing the insulin-like growth factor 2 gene, by binding to the H-19 imprinting control region (ICR) along with differentially-methylated region-1 (DMR1) and MAR3. Binding of targeting sequence elements by CTCF can block the interaction between enhancers and promoters, therefore limiting the activity of enhancers to certain functional domains. Besides acting as enhancer blocking, CTCF can also act as a chromatin barrier by preventing the spread of heterochromatin structures. Synonyms: Monoclonal CTCF antibody, Anti-CTCF antibody, CTC F antibody, CTC-F antibody, Transcriptional repressor CTCF antibody, 11-zinc finger protein antibody, CCCTC-binding factor antibody.