GATA3 Antikörper

Produktnummer ABIN933858

Dieser Anti-GATA3 Antikörper ist ein Ratte Monoklonal Antikörper zur Detektion von GATA3 in WB und IF. Geeignet für Maus.

Kurzübersicht für GATA3 Antikörper (ABIN933858)

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser GATA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: KT77

Produktdetails anti-GATA3 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: GATA3 antibody was raised in Rat using Mouse GATA-3 as the immunogen.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: IF: 1-10 µg/mL, WB: 0.1-1 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Supplied in PBS containing 0.1 % sodium azide as a preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.

Details zu GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Andere Bezeichnung: GATA3

Hintergrund: GATA3 belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA-3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells. GATA-3 was shown to be required for the luminal A type of breast cancer, intertwined in pathways with ER alpha. However, it is also hypothesised that GATA-3 may play tissue specific roles. Synonyms: Monoclonal GATA3 antibody, Anti-GATA3 antibody, GATA 3 antibody, GATA-3 antibody, Trans-acting T-cell specific transcription factor antibody.

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation