BMP7 Antikörper
Kurzübersicht für BMP7 Antikörper (ABIN933774)
Target
Alle BMP7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Protein A affinity chromatography
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Immunogen
- BMP7 antibody was raised in mouse using recombinant human BMP-7/OP-1 as the immunogen.
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Isotyp
- IgG1 kappa
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Applikationshinweise
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ELISA: 2-4 µg/mL
Optimal conditions should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Konzentration
- Lot specific
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Buffer
- Lyophilized from PBS.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
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Andere Bezeichnung
- BMP7
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Hintergrund
- TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures. Synonyms: Monoclonal BMP7 antibody, Anti-BMP7 antibody, BMP-7 antibody, Bone Morphogenetic antibody, 7 antibody,OP-1 antibody.
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Molekulargewicht
- 28.8 kDa (predicted detection band MW)
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Pathways
- Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance
Target
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