Nef Antikörper (FITC)

Produktnummer ABIN933664

Dieses Maus Monoklonal-Antikörper erkennt spezifisch in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human Immunodeficiency Virus (HIV).

Kurzübersicht für Nef Antikörper (FITC) (ABIN933664)

Target: Nef

Reaktivität: Human Immunodeficiency Virus (HIV)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: FITC

Applikation: Western Blotting (WB), ELISA

Klon: 2H12 N-terminus

Produktdetails

Kreuzreaktivität (Details): Reacts with recombinant nef in ELISA and WB.

Reinheit: > 95 % pure

Immunogen: HIV1 Nef antibody (FITC) was raised using purified recombinant nef (HIV-1) produced in E.coli expression system as the immunogen.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:1,000, WB: 1:1,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Supplied lyophilized in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.
Product is photosensitive and should be protected from light.
Dilute only prior to immediate use.

Lagerung: -80 °C

Informationen zur Lagerung: Aliquot and store at -70 °C or lower.

Antigendetails

Target: Nef

Substanzklasse: Viral Protein

Hintergrund: Nef is a early protein that may play a role in optimizing the host cell environment for viral replication without causing apoptosis. Nef enhances virus infectivity and pathogenicity. It down regulates surface MHC I molecules and internalized molecules are sequestered to the trans-Golgi network. The number of cell surface CD4 antigen are decreased by interacting with the Src family kinase LCK thereby inducing LCK CD4 dissociation and by increasing clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation.  . Synonyms: Monoclonal HIV1 Nef antibody, Anti-HIV1 Nef antibody, HIV-1 Nef antibody, 3'ORF antibody, ABIN antibody, ABIN1 antibody,C terminal core protein antibody, F protein antibody, Nef antibody, Negative factor antibody, p27 antibody, VAN antibody.