FCAR
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB21753
unconjugated
Applikationshinweise
FC: 10 µg/mL, IF: 10 µg/mL Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
Lot specific
Buffer
Supplied in PBS containing 0.1 % sodium azide as a preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.
Target
FCAR
(Fc Fragment of IgA, Receptor For (FCAR))
Andere Bezeichnung
CD89
Hintergrund
CD89 is a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Synonyms: Monoclonal CD89 antibody, Anti-CD89 antibody, CD 89 antibody, CD-89 antibody, Fc fragment of IgA receptor antibody, FCAR antibody, Cluster of Differentiation 89 antibody, CD 89 antibody.