RFXAP Antikörper

Produktnummer ABIN932997

Produktdetails anti-RFXAP Antikörper

Target: RFXAP (Regulatory Factor X-Associated Protein (RFXAP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RFXAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Dot Blot (DB)

Kreuzreaktivität: Human, Maus

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: RFXAP antibody was raised in mouse using recombinant Regulatory Factor X-Associated Protein (Rfxap)

Klon: RFXAD55A

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: RFXAP antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 PO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu RFXAP

Target: RFXAP (Regulatory Factor X-Associated Protein (RFXAP))

Andere Bezeichnung: RFXAP (RFXAP Produkte)

Hintergrund: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrincontaining protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. Synonyms: Monoclonal RFXAP antibody, Anti-RFXAP antibody, Regulatory factor X-associated protein antibody.