GATA2 Antikörper
Kurzübersicht für GATA2 Antikörper (ABIN932509)
Target
Alle GATA2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human
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Kreuzreaktivität (Details)
- Other species not studied.
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- GATA2 antibody was raised in mouse using recombinant Human Gata Binding Protein 2
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Isotyp
- IgG2b
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Applikationshinweise
- Optimal conditions should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- Lot specific
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Buffer
- GATA2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- GATA2 (GATA Binding Protein 2 (GATA2))
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Andere Bezeichnung
- GATA2
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Hintergrund
- The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. GATA1 is essential for normal primitive and definitive erythropoiesis and is expressed at high levels in erythroid cells, mast cells, and megakaryocytes. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells. In chicken erythroid progenitors, forced expression of GATA2 promotes proliferation at the expense of differentiation. GATA3 expression is restricted to T-lymphoid cells and some nonhematopoietic cell types, including embryonic stem cells. Synonyms: Monoclonal GATA2 antibody, Anti-GATA2 antibody, GATA binding protein 2 antibody, MGC2306 antibody, NFE1B antibody.
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Pathways
- Stem Cell Maintenance
Target
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