MXI1 Antikörper

Produktnummer ABIN931182

Dieses Anti-MXI1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MXI1 in DB. Geeignet für Human.

Kurzübersicht für MXI1 Antikörper (ABIN931182)

Target: MXI1 (MAX Interactor 1 (MXI1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MXI1 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: MXI1C2a

Produktdetails anti-MXI1 Antikörper

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: MXI1 antibody was raised in mouse using recombinant Human Max Interactor 1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: MXI1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu MXI1

Target: MXI1 (MAX Interactor 1 (MXI1))

Andere Bezeichnung: MXI1

Hintergrund: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Synonyms: Monoclonal MXI1 antibody, Anti-MXI1 antibody, MAX interacting protein 1 antibody, MAD2 antibody, MXD2 antibody, MXI antibody, MGC43220 antibody.

Pathways: Maintenance of Protein Location