E2F5 Antikörper

Produktnummer ABIN931153

Dieses Maus Monoklonal-Antikörper erkennt spezifisch E2F5 in DB und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für E2F5 Antikörper (ABIN931153)

Target: E2F5

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser E2F5 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB), Immunocytochemistry (ICC)

Klon: 220D1a

Produktdetails anti-E2F5 Antikörper

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: E2 F5 antibody was raised in mouse using recombinant Human Transcription Factor E2 -5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: E2 F5 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu E2F5

Target: E2F5

Andere Bezeichnung: E2F5

Hintergrund: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Synonyms: Monoclonal E2F5 antibody, Anti-E2F5 antibody, E2F transcription factor 5 p130-binding antibody.