Paired Box 3 Antikörper
Kurzübersicht für Paired Box 3 Antikörper (ABIN931107)
Target
Alle Paired Box 3 (PAX3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human
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Kreuzreaktivität (Details)
- Other species not studied.
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- PAX3 antibody was raised in mouse using recombinant Human Paired Box Gene 3 (Waardenburg Syndrome 1) (Pax3)
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Isotyp
- IgG1
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Applikationshinweise
- Optimal conditions should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- Lot specific
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Buffer
- PAX3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- Paired Box 3 (PAX3)
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Andere Bezeichnung
- PAX3
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Hintergrund
- This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. Synonyms: Monoclonal PAX3 antibody, Anti-PAX3 antibody, Paired box 3 antibody, WS1 antibody, CDHS antibody, HUP2 antibody, MGC120381 antibody, MGC120382 antibody, MGC120383 antibody, MGC120384 antibody, MGC134778 antibody.
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Pathways
- Sensory Perception of Sound, Tube Formation
Target
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