RHOB Antikörper
Kurzübersicht für RHOB Antikörper (ABIN931074)
Target
Alle RHOB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Kreuzreaktivität
- Human
-
Kreuzreaktivität (Details)
- Other species not studied.
-
Aufreinigung
- Protein G affinity chromatography
-
Immunogen
- RHOB antibody was raised in mouse using recombinant Human Ras Homolog Gene Family, Member B (Rhob)
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
- Optimal conditions should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- Lot specific
-
Buffer
- RHOB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Handhabung
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
-
-
- RHOB (Ras Homolog Gene Family, Member B (RHOB))
-
Andere Bezeichnung
- RHOB
-
Hintergrund
- RHOB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Synonyms: Monoclonal RHOB antibody, Anti-RHOB antibody, Ras homolog gene family member B antibody, ARH6 antibody, ARHB antibody, RHOH6 antibody, MST081 antibody, MSTP081 antibody.
Target
-