AXUD1 Antikörper

Produktnummer ABIN931016

Der Maus Monoklonal Anti-AXUD1-Antikörper wurde für DB validiert. Er ist geeignet, AXUD1 in Proben von Human zu detektieren.

Kurzübersicht für AXUD1 Antikörper (ABIN931016)

Target: AXUD1 (CSRNP1) (Cysteine-serine-Rich Nuclear Protein 1 (CSRNP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AXUD1 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: 2055E3a

Produktdetails anti-AXUD1 Antikörper

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: AXUD1 antibody was raised in mouse using recombinant Human Axin1 Up-Regulated 1 (Axud1)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: AXUD1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu AXUD1

Target: AXUD1 (CSRNP1) (Cysteine-serine-Rich Nuclear Protein 1 (CSRNP1))

Andere Bezeichnung: AXUD1

Hintergrund: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. Synonyms: Monoclonal AXUD1 antibody, Anti-AXUD1 antibody, AXIN1 up regulated 1 antibody, URAX1 antibody, TAIP-3 antibody, DKFZp566F164 antibody, FAM130B antibody.

Pathways: Platelet-derived growth Factor Receptor Signaling