Cyclin T2 Antikörper

Produktnummer ABIN930980

Produktdetails anti-Cyclin T2 Antikörper

Target: Cyclin T2 (CCNT2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cyclin T2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Dot Blot (DB)

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: CCNT2 antibody was raised in mouse using recombinant Human Cyclin T2 (Ccnt2), Transcript Variant B

Klon: 2128C1a

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: CCNT2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu Cyclin T2

Target: Cyclin T2 (CCNT2)

Andere Bezeichnung: CCNT2 (CCNT2 Produkte)

Hintergrund: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. Two alternatively spliced transcript variants, which encode distinct isoforms, have been described. Synonyms: Monoclonal CCNT2 antibody, Anti-CCNT2 antibody, Cyclin T2 antibody, FLJ90560 antibody, MGC134840 antibody.