Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

DMP1 Antikörper

This anti-DMP1 antibody (ABIN930913) is a Mouse Monoclonal antibody detecting DMP1 in DB. Suitable for Human.
Produktnummer ABIN930913

Quick Overview for DMP1 Antikörper (ABIN930913)

Target

Alle DMP1 (DMTF1) Antikörper anzeigen
DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

Reaktivität

  • 81
  • 19
  • 19
  • 8
  • 8
  • 8
  • 7
  • 6
  • 6
  • 5
  • 2
  • 2
  • 2
Human

Wirt

  • 71
  • 7
  • 3
  • 1
Maus

Klonalität

  • 76
  • 6
Monoklonal

Konjugat

  • 36
  • 6
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DMP1 Antikörper ist unkonjugiert

Applikation

  • 57
  • 33
  • 26
  • 26
  • 8
  • 6
  • 5
  • 4
  • 1
Dot Blot (DB)

Klon

DMTF5I250
  • Kreuzreaktivität

    Human

    Kreuzreaktivität (Details)

    Other species not studied.

    Aufreinigung

    Protein G affinity chromatography

    Immunogen

    DMTF1 antibody was raised in mouse using recombinant Cyclin D Binding Myb-Like Transcription Factor 1

    Isotyp

    IgG1
  • Applikationshinweise

    Optimal conditions should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    Lot specific

    Buffer

    DMTF1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3).

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • Target

    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

    Andere Bezeichnung

    DMTF1

    Hintergrund

    This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Synonyms: Monoclonal DMTF1 antibody, Anti-DMTF1 antibody, Cyclin D binding myb-like transcription factor 1 antibody, DMP1 antibody, DMTF antibody, hDMP1 antibody.
Sie sind hier:
Chat with us!