PROX1 Antikörper (C-Term)
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- Target Alle PROX1 Antikörper anzeigen
- PROX1 (Prospero Homeobox 1 (PROX1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PROX1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody will detect Prox-1 in the nucleus of lymphatic endothelial cells by immunostaining, and human Prox 1 by western blot.
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Kreuzreaktivität (Details)
- Equal reactivity with Human, Mouse, and Rat
- Aufreinigung
- Protein A affinity chromatography
- Immunogen
- Prox 1 antibody was raised in rabbit using recombinant human C-terminal part of Prox-1 (homeo domain and prospero domain) as the immunogen
- Isotyp
- IgG
- Top Product
- Discover our top product PROX1 Primärantikörper
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- Applikationshinweise
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WB: 1-5µg/mL. For other applications, optimal conditions should be determined by end-user
Optimal conditions should be determined by the investigator. - Kommentare
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The lyophilized IgG is stable at 4 °C for at least one month and for more than a year when kept at -20 °C. When reconstituted in sterile water to a concentration of >0.5 mg/mL the antibody is stable for at least six weeks at 2-4 °C in the presence of a preservative.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Konzentration
- Lot specific
- Buffer
- IgG fraction supplied lyophilizedfrom PBS, pH 7.4 with no preservative.
- Konservierungsmittel
- Without preservative
- Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store lyophilized antibody at -20 °C. Following reconstitution store at 4 °C in the short-term. For longer term storage aliquot and store at -20 °C or -70 °C.
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EphB4 forward signalling regulates lymphatic valve development." in: Nature communications, Vol. 6, pp. 6625, (2016) (PubMed).
: "Lymphatic ontogeny and effect of hypoplasia in developing lung." in: Mechanisms of development, Vol. 128, Issue 1-2, pp. 29-40, (2011) (PubMed).
: "NFATc1 regulates lymphatic endothelial development." in: Mechanisms of development, Vol. 126, Issue 5-6, pp. 350-65, (2009) (PubMed).
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EphB4 forward signalling regulates lymphatic valve development." in: Nature communications, Vol. 6, pp. 6625, (2016) (PubMed).
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- Target
- PROX1 (Prospero Homeobox 1 (PROX1))
- Andere Bezeichnung
- Prox 1 (PROX1 Produkte)
- Synonyme
- xprox1 antikoerper, prospero antikoerper, PROX1 antikoerper, LOC100232600 antikoerper, A230003G05Rik antikoerper, prox1 antikoerper, zgc:111888 antikoerper, prospero homeobox 1 antikoerper, prospero homeobox 1 L homeolog antikoerper, prospero homeobox 1a antikoerper, PROX1 antikoerper, prox1.L antikoerper, prox1 antikoerper, Prox1 antikoerper, prox1a antikoerper
- Hintergrund
- Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox-1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. Synonyms: Polyclonal Prox 1 antibody, Anti-Prox 1 antibody, Prox-1 antibody, Prospero related homeobox 1 antibody, Homeobox prospero like protein antibody, Homeobox prospero like protein PROX1 antibody, Prospero homeobox protein 1 antibody, Prospero related homeobox 1 antibody.
- Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
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