MRGPRX2 Antikörper (Middle Region)

Produktnummer ABIN929387

Der Kaninchen Polyklonal anti-MRGPRX2 Antikörper wird verwendet zum Nachweis von MRGPRX2 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für MRGPRX2 Antikörper (Middle Region) (ABIN929387)

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGPRX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MRGPRX2 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: MRGPRX2 antibody was raised in rabbit using the middle region of MRGPRX2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

MRGPRX2 Blocking Peptide, (ABIN5614836), is also available for use as a blocking control in assays to test for specificity of this MRGPRX2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu MRGPRX2

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Andere Bezeichnung: MRGPRX2

Hintergrund: MRGPRX2 is an orphan receptor. It probably involved in the function of nociceptive neurons. It also may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca2+ but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. Synonyms: Polyclonal MRGPRX2 antibody, Anti-MRGPRX2 antibody, MAS-related GPR, member X2 antibody, MRGX2 antibody.