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COCH Antikörper (N-Term)

COCH Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN929280
  • Target Alle COCH Antikörper anzeigen
    COCH (Cochlin (COCH))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 48
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 46
    • 2
    Kaninchen
    Klonalität
    • 48
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COCH Antikörper ist unkonjugiert
    Applikation
    • 37
    • 27
    • 16
    • 13
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Aufreinigung
    Purified
    Immunogen
    COCH antibody was raised in rabbit using the N terminal of COCH as the immunogen
    Top Product
    Discover our top product COCH Primärantikörper
  • Applikationshinweise
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    COCH Blocking Peptide, catalog no. 33R-1253, is also available for use as a blocking control in assays to test for specificity of this COCH antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Konzentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    COCH (Cochlin (COCH))
    Andere Bezeichnung
    COCH (COCH Produkte)
    Synonyme
    AW122937 antikoerper, Coch-5B2 antikoerper, D12H14S564E antikoerper, COCH-5B2 antikoerper, COCH5B2 antikoerper, DFNA9 antikoerper, cochlin antikoerper, Coch antikoerper, COCH antikoerper
    Hintergrund
    The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. Synonyms: Polyclonal COCH antibody, Anti-COCH antibody, coagulation factor C homolog, cochlin, Limulus polyphemus antibody, COCH-5B2 antibody, COCH5B2 antibody, DFNA9 antibody.
    Pathways
    Sensory Perception of Sound
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