RECK Antikörper (Middle Region)

Produktnummer ABIN929166

Produktdetails anti-RECK Antikörper

Target: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RECK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus

Aufreinigung: Purified

Immunogen: Reck antibody was raised in rabbit using the middle region of Reck as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

Reck Blocking Peptide, catalog no. 33R-8331, is also available for use as a blocking control in assays to test for specificity of this Reck antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu RECK

Target: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Andere Bezeichnung: Reck (RECK Produkte)

Synonyme: ST15 antikoerper, St15 antikoerper, mRECK antikoerper, reversion inducing cysteine rich protein with kazal motifs antikoerper, reversion-inducing-cysteine-rich protein with kazal motifs antikoerper, RECK antikoerper, Reck antikoerper

Hintergrund: Reck negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. It appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression. Synonyms: Polyclonal Reck antibody, Anti-Reck antibody, reversion-inducing-cysteine-rich protein with kazal motifs antibody, MGC169689 antibody, St15 antibody, mRECK antibody.