CD8 alpha Antikörper (Middle Region)

Produktnummer ABIN929133

Dieses Anti-CD8 alpha-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD8 alpha in WB. Geeignet für Human.

Kurzübersicht für CD8 alpha Antikörper (Middle Region) (ABIN929133)

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD8 alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD8 alpha Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: CD8 A antibody was raised in rabbit using the middle region of CD8 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CD8A Blocking Peptide, (ABIN5612763), is also available for use as a blocking control in assays to test for specificity of this CD8A antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CD8 alpha

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Andere Bezeichnung: CD8A

Hintergrund: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal CD8A antibody, Anti-CD8A antibody, CD8a molecule antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody.

Pathways: T-Zell Rezeptor Signalweg