NCF4 Antikörper (C-Term)

Produktnummer ABIN929086

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NCF4 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NCF4 Antikörper (C-Term) (ABIN929086)

Target: NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NCF4 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: NCF4 antibody was raised in rabbit using the C terminal of NCF4 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

NCF4 Blocking Peptide, (ABIN5614928), is also available for use as a blocking control in assays to test for specificity of this NCF4 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu NCF4

Target: NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))

Andere Bezeichnung: NCF4

Hintergrund: NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. Synonyms: Polyclonal NCF4 antibody, Anti-NCF4 antibody, neutrophil cytosolic factor 4, 40kDa antibody, MGC3810 antibody, NCF antibody, P40PHOX antibody, SH3PXD4 antibody.