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Glutaredoxin 2 Antikörper (Middle Region)

GRX2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN929001
  • Target Alle Glutaredoxin 2 (GRX2) Antikörper anzeigen
    Glutaredoxin 2 (GRX2)
    Bindungsspezifität
    • 16
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 41
    • 23
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 35
    • 6
    Kaninchen
    Klonalität
    • 39
    • 2
    Polyklonal
    Konjugat
    • 21
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Glutaredoxin 2 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 21
    • 13
    • 13
    • 10
    • 9
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Aufreinigung
    Purified
    Immunogen
    GLRX2 antibody was raised in rabbit using the middle region of GLRX2 as the immunogen
    Top Product
    Discover our top product GRX2 Primärantikörper
  • Applikationshinweise
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    GLRX2 Blocking Peptide, catalog no. 33R-6922, is also available for use as a blocking control in assays to test for specificity of this GLRX2 antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Konzentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    Glutaredoxin 2 (GRX2)
    Andere Bezeichnung
    GLRX2 (GRX2 Produkte)
    Synonyme
    ECK1049 antikoerper, JW1051 antikoerper, CGI-133 antikoerper, GRX2 antikoerper, 1700010P22Rik antikoerper, AI645710 antikoerper, Grx2 antikoerper, glutaredoxin 2 (Grx2) antikoerper, glutaredoxin Grx2 antikoerper, thioredoxin antikoerper, glutaredoxin 2 antikoerper, glutaredoxin 2 (thioltransferase) antikoerper, grxB antikoerper, grx2 antikoerper, AF_RS10790 antikoerper, GLRX2 antikoerper, Glrx2 antikoerper
    Hintergrund
    GLRX2 is a glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress.GLRX2 is involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress.GLRX2 acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides.GLRX2 can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions.GLRX2 efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Synonyms: Polyclonal GLRX2 antibody, Anti-GLRX2 antibody, glutaredoxin 2 antibody, GRX2 antibody, bA101E13.1 antibody.
    Pathways
    Cell RedoxHomeostasis
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