Glutaredoxin 2 Antikörper (Middle Region)

Produktnummer ABIN929001

Dieses Anti-Glutaredoxin 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Glutaredoxin 2 in WB. Geeignet für Human.

Kurzübersicht für Glutaredoxin 2 Antikörper (Middle Region) (ABIN929001)

Target: Glutaredoxin 2 (GRX2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutaredoxin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Glutaredoxin 2 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: GLRX2 antibody was raised in rabbit using the middle region of GLRX2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

GLRX2 Blocking Peptide, (ABIN5613785), is also available for use as a blocking control in assays to test for specificity of this GLRX2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Glutaredoxin 2

Target: Glutaredoxin 2 (GRX2)

Andere Bezeichnung: GLRX2

Hintergrund: GLRX2 is a glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress.GLRX2 is involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress.GLRX2 acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides.GLRX2 can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions.GLRX2 efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Synonyms: Polyclonal GLRX2 antibody, Anti-GLRX2 antibody, glutaredoxin 2 antibody, GRX2 antibody, bA101E13.1 antibody.

Pathways: Cell RedoxHomeostasis