NARF Antikörper (Middle Region)

Produktnummer ABIN928727

Der Kaninchen Polyklonal anti-NARF Antikörper wird verwendet zum Nachweis von NARF in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für NARF Antikörper (Middle Region) (ABIN928727)

Target: NARF (Nuclear Prelamin A Recognition Factor (NARF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NARF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NARF Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: NARF antibody was raised in rabbit using the middle region of NARF as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

NARF Blocking Peptide, (ABIN5614915), is also available for use as a blocking control in assays to test for specificity of this NARF antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu NARF

Target: NARF (Nuclear Prelamin A Recognition Factor (NARF))

Andere Bezeichnung: NARF

Hintergrund: Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. NARF binds to the prenylated prelamin A carboxyl-terminal tail domain. Synonyms: Polyclonal NARF antibody, Anti-NARF antibody, nuclear prelamin A recognition factor antibody, DKFZp434G0420 antibody, FLJ10067 antibody, IOP2 antibody.