PYHIN1 Antikörper (N-Term)
Kurzübersicht für PYHIN1 Antikörper (N-Term) (ABIN928476)
Target
Alle PYHIN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- N-Term
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                                            Kreuzreaktivität
- Maus, Ratte (Rattus), Rind (Kuh), Hund
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                                            Aufreinigung
- Purified
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                                            Immunogen
- PYHIN1 antibody was raised in rabbit using the N terminal of PYHIN1 as the immunogen
 
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                                            Applikationshinweise
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                        WB: 0.2-1 µg/mL
 Optimal conditions should be determined by the investigator.
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                                            Kommentare
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                        PYHIN1 Blocking Peptide, (ABIN936790), is also available for use as a blocking control in assays to test for specificity of this PYHIN1 antibody 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Lyophilized
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                                            Konzentration
- Lot specific
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                                            Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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                                            Handhabung
- Avoid repeated freeze/thaw cycles.
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                                            Lagerung
- 4 °C/-20 °C
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                                            Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
 
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    - PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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                                            Andere Bezeichnung
- PYHIN1
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                                            Hintergrund
- PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells. Synonyms: Polyclonal PYHIN1 antibody, Anti-PYHIN1 antibody, pyrin and HIN domain family, member 1 antibody, IFIX antibody, MGC23885 antibody, RP11-520H16.1 antibody.
 Target
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