PYHIN1 Antikörper (N-Term)
Kurzübersicht für PYHIN1 Antikörper (N-Term) (ABIN928476)
Target
Alle PYHIN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Kreuzreaktivität
- Maus, Ratte (Rattus), Rind (Kuh), Hund
-
Aufreinigung
- Purified
-
Immunogen
- PYHIN1 antibody was raised in rabbit using the N terminal of PYHIN1 as the immunogen
-
-
-
-
Applikationshinweise
-
WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
-
PYHIN1 Blocking Peptide, catalog no. 33R-1404, is also available for use as a blocking control in assays to test for specificity of this PYHIN1 antibody
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Konzentration
- Lot specific
-
Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
-
Handhabung
- Avoid repeated freeze/thaw cycles.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
-
-
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
-
Andere Bezeichnung
- PYHIN1
-
Hintergrund
- PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells. Synonyms: Polyclonal PYHIN1 antibody, Anti-PYHIN1 antibody, pyrin and HIN domain family, member 1 antibody, IFIX antibody, MGC23885 antibody, RP11-520H16.1 antibody.
Target
-