PSMC3IP Antikörper (C-Term)

Produktnummer ABIN928182

Dieser Anti-PSMC3IP Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von PSMC3IP in WB. Geeignet für Maus, Human, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Huhn und Xenopus laevis.

Kurzübersicht für PSMC3IP Antikörper (C-Term) (ABIN928182)

Target: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Reaktivität: Maus, Human, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC3IP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PSMC3IP Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Frosch, Hund, Huhn, Rind (Kuh), Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: PSMC3 IP antibody was raised in rabbit using the C terminal of PSMC3 P as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

PSMC3IP Blocking Peptide, (ABIN5615629), is also available for use as a blocking control in assays to test for specificity of this PSMC3IP antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PSMC3IP

Target: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Andere Bezeichnung: PSMC3IP

Hintergrund: PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. Synonyms: Polyclonal PSMC3IP antibody, Anti-PSMC3IP antibody, PSMC3 interacting protein antibody, GT198 antibody, HOP2 antibody, TBPIP antibody.