RAG1 Antikörper (C-Term)

Produktnummer ABIN928010

Der Kaninchen Polyklonal Anti-RAG1-Antikörper wurde für WB validiert. Er ist geeignet, RAG1 in Proben von Maus und Human zu detektieren.

Kurzübersicht für RAG1 Antikörper (C-Term) (ABIN928010)

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Reaktivität: Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAG1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Maus

Aufreinigung: Purified

Immunogen: Rag1 antibody was raised in rabbit using the C terminal of Rag1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

Rag1 Blocking Peptide, catalog no. 33R-3994, is also available for use as a blocking control in assays to test for specificity of this Rag1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu RAG1

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Andere Bezeichnung: Rag1

Hintergrund: As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. Synonyms: Polyclonal Rag1 antibody, Anti-Rag1 antibody, recombination activating gene 1 antibody, Rag-1 antibody.