Amylin/DAP Antikörper (N-Term)

Produktnummer ABIN927970

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Amylin/DAP in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Amylin/DAP Antikörper (N-Term) (ABIN927970)

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Amylin/DAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Amylin/DAP Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified

Immunogen: IAPP antibody was raised in rabbit using the N terminal of IAPP as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

IAPP Blocking Peptide, (ABIN5614120), is also available for use as a blocking control in assays to test for specificity of this IAPP antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Amylin/DAP

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Andere Bezeichnung: IAPP

Hintergrund: Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. Synonyms: Polyclonal IAPP antibody, Anti-IAPP antibody, islet amyloid polypeptide antibody, AMYLIN antibody, DAP antibody, IAP antibody.

Pathways: Hormone Activity, Feeding Behaviour