KEAP1 Antikörper (C-Term)

Produktnummer ABIN927752

Der Kaninchen Polyklonal Anti-KEAP1 Antikörper wurde für WB und IHC validiert. Er ist geeignet, KEAP1 in Proben von Human, Maus, Ratte, Schwein, Rind (Kuh) und Xenopus laevis zu detektieren.

Kurzübersicht für KEAP1 Antikörper (C-Term) (ABIN927752)

Target: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KEAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-KEAP1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Schwein, Frosch

Aufreinigung: Purified

Immunogen: KEAP1 antibody was raised in rabbit using the C terminal of KEAP1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

KEAP1 Blocking Peptide, (ABIN939247), is also available for use as a blocking control in assays to test for specificity of this KEAP1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu KEAP1

Target: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Andere Bezeichnung: KEAP1

Hintergrund: KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests. Synonyms: Polyclonal KEAP1 antibody, Anti-KEAP1 antibody, kelch-like ECH-associated protein 1 antibody.

Pathways: Maintenance of Protein Location