RBM5 Antikörper (N-Term)

Produktnummer ABIN927731

Der Kaninchen Polyklonal Anti-RBM5-Antikörper wurde für WB validiert. Er ist geeignet, RBM5 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Huhn und Xenopus laevis zu detektieren.

Kurzübersicht für RBM5 Antikörper (N-Term) (ABIN927731)

Target: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RBM5 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund, Frosch, Huhn

Aufreinigung: Purified

Immunogen: RBM5 antibody was raised in rabbit using the N terminal of RBM5 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

RBM5 Blocking Peptide, (ABIN938939), is also available for use as a blocking control in assays to test for specificity of this RBM5 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu RBM5

Target: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Andere Bezeichnung: RBM5

Hintergrund: RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis. Synonyms: Polyclonal RBM5 antibody, Anti-RBM5 antibody, RNA binding motif protein 5 antibody, FLJ39876 antibody, G15 antibody, H37 antibody, LUCA15 antibody, RMB5 antibody.

Pathways: Ribonucleoprotein Complex Subunit Organization