APP Antikörper (C-Term)

Produktnummer ABIN927396

Der Kaninchen Polyklonal anti-APP Antikörper (ABIN927396) detektiert spezifisch APP in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für APP Antikörper (C-Term) (ABIN927396)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-APP Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Maus

Aufreinigung: Purified

Immunogen: App antibody was raised in rabbit using the C terminal of App as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

App Blocking Peptide, (ABIN938182), is also available for use as a blocking control in assays to test for specificity of this App antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Andere Bezeichnung: App

Hintergrund: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a  number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of  patients with Alzheimer disease. Synonyms: Polyclonal App antibody, Anti-App antibody, amyloid beta, A4 precursor protein antibody, Ag antibody, Abpp antibody, Adap antibody, Cvap antibody, Abeta antibody, betaApp antibody, AL024401 antibody, E030013M08Rik antibody, App antibody.

Pathways: Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour