Estrogen Receptor alpha Antikörper (C-Term)

Produktnummer ABIN927316

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Estrogen Receptor alpha in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Estrogen Receptor alpha Antikörper (C-Term) (ABIN927316)

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Estrogen Receptor alpha Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: ESR1 antibody was raised in rabbit using the C terminal of ESR1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

ESR1 Blocking Peptide, (ABIN940517), is also available for use as a blocking control in assays to test for specificity of this ESR1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Estrogen Receptor alpha

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Andere Bezeichnung: ESR1

Hintergrund: ESR1 is an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. Synonyms: Polyclonal ESR1 antibody, Anti-ESR1 antibody, estrogen receptor 1 antibody, DKFZp686N23123 antibody, ER antibody, ESR antibody, ESRA antibody, Era antibody, NR3A1 antibody.

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly