Cyclin T1 Antikörper (N-Term)

Produktnummer ABIN926896

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cyclin T1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Xenopus laevis und Zebrafisch (Danio rerio).

Kurzübersicht für Cyclin T1 Antikörper (N-Term) (ABIN926896)

Target: Cyclin T1 (CCNT1)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Xenopus laevis, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin T1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Cyclin T1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund, Frosch, Schwein, Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: CCNT1 antibody was raised in rabbit using the N terminal of CCNT1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CCNT1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CCNT1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Cyclin T1

Target: Cyclin T1 (CCNT1)

Andere Bezeichnung: CCNT1

Hintergrund: CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. Synonyms: Polyclonal CCNT1 antibody, Anti-CCNT1 antibody, cyclin T1 antibody, CCNT antibody, CYCT1 antibody.