SCARB2 Antikörper (N-Term)

Produktnummer ABIN926775

Dieses Anti-SCARB2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SCARB2 in WB. Geeignet für Human.

Kurzübersicht für SCARB2 Antikörper (N-Term) (ABIN926775)

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCARB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SCARB2 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified

Immunogen: SCARB2 antibody was raised in rabbit using the N terminal of SCARB2 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

SCARB2 Blocking Peptide, catalog no. 33R-10420, is also available for use as a blocking control in assays to test for specificity of this SCARB2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu SCARB2

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Andere Bezeichnung: SCARB2

Hintergrund: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Synonyms: Polyclonal SCARB2 antibody, Anti-SCARB2 antibody, scavenger receptor class B, member 2 antibody, AMRF antibody, CD36L2 antibody, HLGP85 antibody, LIMPII antibody, SR-BII antibody.