RPL7 Antikörper (C-Term)

Produktnummer ABIN926766

Produktdetails anti-RPL7 Antikörper

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPL7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: RPL7 antibody was raised in rabbit using the C terminal of RPL7 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

RPL7 Blocking Peptide, catalog no. 33R-10269, is also available for use as a blocking control in assays to test for specificity of this RPL7 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu RPL7

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Andere Bezeichnung: RPL7 (RPL7 Produkte)

Hintergrund: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Synonyms: Polyclonal RPL7 antibody, Anti-RPL7 antibody, ribosomal protein L7 antibody, MGC117326 antibody, humL7-1 antibody.