GALR2 Antikörper (C-Term)

Produktnummer ABIN926733

Dieses Anti-GALR2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GALR2 in WB. Geeignet für Human.

Kurzübersicht für GALR2 Antikörper (C-Term) (ABIN926733)

Target: GALR2 (Galanin Receptor 2 (GALR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GALR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GALR2 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: GALR2 antibody was raised in rabbit using the C terminal of GALR2 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

GALR2 Blocking Peptide, (ABIN936382), is also available for use as a blocking control in assays to test for specificity of this GALR2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu GALR2

Target: GALR2 (Galanin Receptor 2 (GALR2))

Andere Bezeichnung: GALR2

Hintergrund: Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. Synonyms: Polyclonal GALR2 antibody, Anti-GALR2 antibody, galanin receptor 2 antibody, GALNR2 antibody, MGC125983 antibody, MGC125984 antibody.

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour