GBA Antikörper (C-Term)
Kurzübersicht für GBA Antikörper (C-Term) (ABIN926718)
Target
Alle GBA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Aufreinigung
- Purified
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Immunogen
- GBA antibody was raised in rabbit using the C terminal of GBA as the immunogen
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Applikationshinweise
- Optimal conditions should be determined by the investigator.
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Kommentare
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GBA Blocking Peptide, (ABIN936300), is also available for use as a blocking control in assays to test for specificity of this GBA antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Konzentration
- Lot specific
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Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- GBA (Glucosidase, Beta, Acid (GBA))
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Andere Bezeichnung
- GBA
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Hintergrund
- This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. Synonyms: Polyclonal GBA antibody, Anti-GBA antibody, glucosidase, beta, acid antibody, GBA1 antibody, GCB antibody, GLUC antibody.
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Pathways
- Cellular Glucan Metabolic Process
Target
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