NQO1 Antikörper (Middle Region)

Produktnummer ABIN926681

Der Kaninchen Polyklonal Anti-NQO1-Antikörper wurde für WB validiert. Er ist geeignet, NQO1 in Proben von Human zu detektieren.

Kurzübersicht für NQO1 Antikörper (Middle Region) (ABIN926681)

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NQO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NQO1 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: NQO1 antibody was raised in rabbit using the middle region of NQO1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

NQO1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this NQO1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu NQO1

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Andere Bezeichnung: NQO1

Hintergrund: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Synonyms: Polyclonal NQO1 antibody, Anti-NQO1 antibody, NADPH dehydrogenase, quinone 1 antibody, DHQU antibody, DIA4 antibody, DTD antibody, NMOR1 antibody, NMORI antibody, QR1 antibody.